Question: Which SSRI Has The Least Side Effects?

Which SSRI is easiest to withdraw from?

Fluoxetine, which has the longest half-life of the SSRIs (see Table 1), appears to produce the fewest withdrawal symptoms, while paroxetine, which has the shortest half-life, produces the most pronounced discontinuation effects..

Which is the newest antidepressant?

On March 5, the Food and Drug Administration (FDA) approved the first truly new medication for major depression in decades. The drug is a nasal spray called esketamine, derived from ketamine—an anesthetic that has made waves for its surprising antidepressant effect.

What is the hardest antidepressant to come off of?

Hardest-to-Stop Antidepressantscitalopram) (Celexa)escitalopram (Lexapro)paroxetine (Paxil)sertraline (Zoloft)

Which antidepressants have the least side effects?

Selective serotonin reuptake inhibitors (SSRIs). Doctors often start by prescribing an SSRI . These medications generally cause fewer bothersome side effects and are less likely to cause problems at higher therapeutic doses than other types of antidepressants are.

What is the safest antidepressant?

The results showed the most acceptable antidepressants were agomelatine, citalopram, escitalopram, fluoxetine, sertraline, and vortioxetine; least acceptable (ones with the highest dropout rates) were amitriptyline, clomipramine, duloxetine, fluvoxamine, reboxetine, trazodone, and venlafaxine.

What is the most energizing antidepressant?

Prozac (fluoxetine) and Wellbutrin (bupropion) are examples of “energizing” antidepressants; whereas Paxil (paroxetine) and Celexa (citalopram) tend to be more sedating.

What is the most commonly prescribed antidepressant?

Selective serotonin reuptake inhibitors (SSRIs) are the most prescribed type of antidepressant and include:Fluoxetine.Citalopram.Sertraline.Paroxetine.Escitalopram.

What is a drug that calms you down?

Benzodiazepines are also called minor tranquillizers, sedatives or hypnotics. They are the most widely prescribed psychoactive drugs in the world. The calming effects of benzodiazepines can often be achieved without drugs.

What does SSRI withdrawal feel like?

The most common symptoms of SSRI discontinuation syndrome are described as either being flu-like, or feeling like a sudden return of anxiety or depression. 1 They include: Dizziness. Vertigo.

What is a brain zap?

Brain zaps are electrical shock sensations in the brain. They can happen in a person who is decreasing or stopping their use of certain medications, particularly antidepressants. Brain zaps are not harmful and will not damage the brain. However, they can be bothersome, disorienting, and disruptive to sleep.

Which SSRI is best tolerated?

Overall, citalopram appears to be the best-tolerated SSRI, followed by fluoxetine, sertraline, paroxetine, and fluvoxamine. The latter 2 drugs are associated with the most side effects and the highest discontinuation rates because of side effects in clinical trials.